Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Emcn  endomucin   (Synonyms: 0610012K22Rik)
Results	Reference
1	J:237340 Ben Shoham A, Rot C, Stern T, Krief S, Akiva A, Dadosh T, Sabany H, Lu Y, Kadler KE, Zelzer E, Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology. Development. 2016 Nov 01;143(21):3933-3943
1	J:330573 Bonet F, Anez SB, Inacio JM, Futschik ME, Belo JA, CCBE1 Is Essential for Epicardial Function during Myocardium Development. Int J Mol Sci. 2022 Oct 20;23(20)
1	J:345820 Cardarelli S, Biglietto M, Orsini T, Fustaino V, Monaco L, de Oliveira do Rego AG, Liccardo F, Masciarelli S, Fazi F, Naro F, De Angelis L, Pellegrini M, Modulation of cAMP/cGMP signaling as prevention of congenital heart defects in Pde2A deficient embryos: a matter of oxidative stress. Cell Death Dis. 2024 Feb 23;15(2):169
1	J:344154 Carlantoni C, Liekfeld LMH, Hemkemeyer SA, Schreier D, Saygi C, Kurelic R, Cardarelli S, Kalucka J, Schulte C, Beerens M, Mailer RK, Schaffer TE, Naro F, Pellegrini M, Nikolaev VO, Renne T, Frye M, The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling. Dev Cell. 2023 Dec 23;
1	J:233304 Cha B, Geng X, Mahamud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon JB, Chen H, Srinivasan RS, Mechanotransduction activates canonical Wnt/beta-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves. Genes Dev. 2016 Jun 15;30(12):1454-69
1	J:301556 Cha B, Ho YC, Geng X, Mahamud MR, Chen L, Kim Y, Choi D, Kim TH, Randolph GJ, Cao X, Chen H, Srinivasan RS, YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling. Development. 2020 Dec 13;147(23):dev195453
1	J:333725 Chiang IKN, Graus MS, Kirschnick N, Davidson T, Luu W, Harwood R, Jiang K, Li B, Wong YY, Moustaqil M, Lesieur E, Skoczylas R, Kouskoff V, Kazenwadel J, Arriola-Martinez L, Sierecki E, Gambin Y, Alitalo K, Kiefer F, Harvey NL, Francois M, The blood vasculature instructs lymphatic patterning in a SOX7-dependent manner. EMBO J. 2023 Mar 1;42(5):e109032
1	J:207983 D'Amico G, Korhonen EA, Anisimov A, Zarkada G, Holopainen T, Hagerling R, Kiefer F, Eklund L, Sormunen R, Elamaa H, Brekken RA, Adams RH, Koh GY, Saharinen P, Alitalo K, Tie1 deletion inhibits tumor growth and improves angiopoietin antagonist therapy. J Clin Invest. 2014 Feb 3;124(2):824-34
1	J:159507 D'Amico G, Korhonen EA, Waltari M, Saharinen P, Laakkonen P, Alitalo K, Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report. Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):207-9
1	J:341659 Fernandes LM, Tresemer J, Zhang J, Rios JJ, Scallan JP, Dellinger MT, Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function. Front Cell Dev Biol. 2023;11:1276333
1	J:210076 Greulich F, Farin HF, Schuster-Gossler K, Kispert A, Tbx18 function in epicardial development. Cardiovasc Res. 2012 Dec 1;96(3):476-83
1	J:337033 Greulich F, Rudat C, Farin HF, Christoffels VM, Kispert A, Lack of Genetic Interaction between Tbx18 and Tbx2/Tbx20 in Mouse Epicardial Development. PLoS One. 2016;11(6):e0156787
1	J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23
1	J:252596 Janardhan HP, Milstone ZJ, Shin M, Lawson ND, Keaney JF Jr, Trivedi CM, Hdac3 regulates lymphovenous and lymphatic valve formation. J Clin Invest. 2017 Nov 1;127(11):4193-4206
1*	J:244466 Karpanen T, Padberg Y, van de Pavert SA, Dierkes C, Morooka N, Peterson-Maduro J, van de Hoek G, Adrian M, Mochizuki N, Sekiguchi K, Kiefer F, Schulte D, Schulte-Merker S, An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation. Circ Res. 2017 Apr 14;120(8):1263-1275
1	J:340487 Kazenwadel J, Venugopal P, Oszmiana A, Toubia J, Arriola-Martinez L, Panara V, Piltz SG, Brown C, Ma W, Schreiber AW, Koltowska K, Taoudi S, Thomas PQ, Scott HS, Harvey NL, A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature. Nature. 2023 Feb;614(7947):343-348
1	J:263031 Kontarakis Z, Rossi A, Ramas S, Dellinger MT, Stainier DYR, Mir-126 is a conserved modulator of lymphatic development. Dev Biol. 2018 May 15;437(2):120-130
1*	J:207611 Lange AW, Haitchi HM, LeCras TD, Sridharan A, Xu Y, Wert SE, James J, Udell N, Thurner PJ, Whitsett JA, Sox17 is required for normal pulmonary vascular morphogenesis. Dev Biol. 2014 Mar 1;387(1):109-20
1	J:250555 Langen UH, Pitulescu ME, Kim JM, Enriquez-Gasca R, Sivaraj KK, Kusumbe AP, Singh A, Di Russo J, Bixel MG, Zhou B, Sorokin L, Vaquerizas JM, Adams RH, Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Nat Cell Biol. 2017 Mar;19(3):189-201
1	J:322701 Liu Y, Chen Q, Jeong HW, Koh BI, Watson EC, Xu C, Stehling M, Zhou B, Adams RH, A specialized bone marrow microenvironment for fetal haematopoiesis. Nat Commun. 2022 Mar 14;13(1):1327
1	J:335167 Lu P, Wu B, Wang Y, Russell M, Liu Y, Bernard DJ, Zheng D, Zhou B, Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. Dev Cell. 2023 Mar 29;
1	J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189
1	J:306259 Luo W, Garcia-Gonzalez I, Fernandez-Chacon M, Casquero-Garcia V, Sanchez-Munoz MS, Muhleder S, Garcia-Ortega L, Andrade J, Potente M, Benedito R, Arterialization requires the timely suppression of cell growth. Nature. 2021 Jan;589(7842):437-441
1	J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381
1	J:330583 McKey J, Anbarci DN, Bunce C, Ontiveros AE, Behringer RR, Capel B, Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii. Elife. 2022 Sep 27;11:e81088
1	J:211806 Outeda P, Huso DL, Fisher SA, Halushka MK, Kim H, Qian F, Germino GG, Watnick T, Polycystin signaling is required for directed endothelial cell migration and lymphatic development. Cell Rep. 2014 May 8;7(3):634-44
1	J:286013 Outhwaite JE, Patel J, Simmons DG, Secondary Placental Defects in Cxadr Mutant Mice. Front Physiol. 2019;10:622
1	J:195902 Rossdeutsch A, Smart N, Dube KN, Turner M, Riley PR, Essential role for thymosin beta4 in regulating vascular smooth muscle cell development and vessel wall stability. Circ Res. 2012 Aug 3;111(4):e89-102
1	J:245879 Tischfield MA, Robson CD, Gilette NM, Chim SM, Sofela FA, DeLisle MM, Gelber A, Barry BJ, MacKinnon S, Dagi LR, Nathans J, Engle EC, Cerebral Vein Malformations Result from Loss of Twist1 Expression and BMP Signaling from Skull Progenitor Cells and Dura. Dev Cell. 2017 Sep 11;42(5):445-461.e5
1	J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977
1	J:344556 Whitchurch JB, Schneider S, Hilger AC, Kollges R, Stegmann JD, Waffenschmidt L, Dyer L, Thiele H, Dhabhai B, Dakal TC, Muller A, Norris DP, Reutter HM, PKD1L1 Is Involved in Congenital Chylothorax. Cells. 2024 Jan 12;13(2)
1	J:306543 Yu Z, Zeng J, Wang J, Cui Y, Song X, Zhang Y, Cheng X, Hou N, Teng Y, Lan Y, Chen Y, Yang X, Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability. Cardiovasc Res. 2021 Jan 21;117(2):533-546
1	J:261328 Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H, Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110